Consider it. You've got:
- sword fights
- immersive fictional society
- extreme environments and creatures
- opportunities for trippy, stretch-the-medium animation effects, thanks to all the drugs floating around
- eccentric antagonists
- general edginess and intensity
- tracts of introspection
- political maneuvering
I see the potential for a perfect marriage. Fans would cry out in anguish, no doubt, fearing that their classic would lose its legitimacy. Maybe you would fear the same? I, however, see potential. After all, we anime fans... we nerds, rather, are often a very fastidious bunch when it comes to honoring the source material.
On a related note, has there ever been an video interpretation to get Dune right? I heard the 80's miniseries was decent but I've never seen it.
Though I will add that the 80's movie has the edginess and exoticism down well. It just... well, you probably already know.
Interesting German sketches from back in the day.